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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Jeff Locke | 1.314 | 2044 | |
| 2 | José Nieves | 1.885 | 2042 | |
| 3 | José Ortega | 1.976 | 2042 | |
| 4 | Lonnie McCardle | 1.979 | 2050 | |
| 5 | Jeff Locke | 2.045 | 2043 | |
| 6 | Quentin Knox | 2.136 | 2048 | |
| 6 | David López | 2.136 | 2029 | |
| 8 | José Nieves | 2.151 | 2040 | |
| 9 | Marv Potts | 2.187 | 2051 | |
| 10 | António Esparza | 2.189 | 2049 | |
| 11 | Chad Jennings | 2.274 | 2040 | |
| 12 | Phil Stoddart# | 2.283 | 2052 | |
| 13 | Jim Hodges | 2.301 | 2036 | |
| 14 | Conor Belk# | 2.312 | 2061 | |
| 15 | José Villarino | 2.332 | 2027 | |
| 16 | Louwe Roocke | 2.344 | 2023 | |
| 17 | Luis Ayala# | 2.361 | 2055 | |
| 18 | Tommy Green | 2.371 | 2024 | |
| 19 | Daniel León | 2.374 | 2041 | |
| 19 | Neil Hardy# | 2.374 | 2058 | |
| 21 | José Nieves | 2.382 | 2043 | |
| 22 | José Ávila | 2.384 | 2031 | |
| 23 | Arturo García | 2.386 | 2049 | |
| 24 | Chad Black | 2.396 | 2045 | |
| 25 | Edwin Hoekstra# | 2.411 | 2052 | |
| 26 | Sinisa Uskokovic# | 2.435 | 2058 | |
| 27 | Sancho Gonzáles | 2.450 | 2025 | |
| 28 | Stan Manning | 2.465 | 2051 | |
| 29 | Bernardo Lanfranchi# | 2.470 | 2064 | |
| 30 | José Ordóñez | 2.474 | 2044 | |
| 31 | Tony Stanley | 2.477 | 2043 | |
| 32 | Toshimichi Yoshida# | 2.507 | 2056 | |
| 33 | Ricky Aguero# | 2.510 | 2065 | |
| 34 | Joe Miller | 2.550 | 2026 | |
| 35 | Dave Harris | 2.555 | 2049 | |
| 36 | Joaquín Martínez | 2.569 | 2028 | |
| 37 | Oscar Gomez# | 2.574 | 2060 | |
| 38 | Lou Hastings | 2.579 | 2047 | |
| 39 | Mamoru Fujihara | 2.582 | 2046 | |
| 40 | Steve Chapman | 2.586 | 2043 | |
| 41 | Adam Booth# | 2.602 | 2055 | |
| 42 | Geoffrey McCluskey | 2.604 | 2041 | |
| 43 | Juan Gonzáles | 2.624 | 2050 | |
| 44 | Jamie Martin | 2.626 | 2025 | |
| 45 | António Villasol | 2.651 | 2043 | |
| 46 | Víctor Alvarado# | 2.657 | 2052 | |
| 47 | Jerry Sánchez | 2.665 | 2022 | |
| 48 | Josh Wallace# | 2.673 | 2058 | |
| 49 | Dan Cunningham | 2.685 | 2042 | |
| 50 | Ho Li# | 2.688 | 2064 | |
| 50 | Dong-po Zhang | 2.688 | 2027 | |
| 52 | Juan Gutiérrez# | 2.700 | 2054 | |
| 52 | Jon Mitchell# | 2.700 | 2060 | |
| 54 | Lou Harvey# | 2.711 | 2050 | |
| 55 | Steve Callahan# | 2.712 | 2058 | |
| 56 | Albert Valverde | 2.718 | 2048 | |
| 57 | Harry Paul# | 2.721 | 2057 | |
| 58 | Ernesto Ramírez | 2.723 | 2043 | |
| 59 | José Calderón | 2.725 | 2044 | |
| 60 | Cereneo Agdeppa | 2.738 | 2031 | |
| 61 | Leonardo Palmer | 2.757 | 2046 | |
| 62 | Shaun Johnston | 2.758 | 2016 | |
| 62 | Razan Tanaka | 2.758 | 2047 | |
| 64 | Jorge Pérez | 2.769 | 2042 | |
| 65 | Tim Kelly | 2.774 | 2018 | |
| 66 | Habbo Buys | 2.789 | 2043 | |
| 67 | Kevin Brooks | 2.793 | 2039 | |
| 67 | David Sánchez | 2.793 | 2022 | |
| 69 | Víctor Gabriel | 2.801 | 2044 | |
| 70 | Danny Jones | 2.803 | 2044 | |
| 71 | Lúcio Hernández | 2.805 | 2037 | |
| 72 | Chad MacPherson# | 2.807 | 2056 | |
| 73 | Héctor Maldonado | 2.814 | 2031 | |
| 74 | Shawn O'Reilly | 2.827 | 2048 | |
| 75 | César Farías | 2.848 | 2023 | |
| 76 | Alex Bond | 2.852 | 2029 | |
| 77 | Randy Lynch | 2.858 | 2047 | |
| 78 | Tony Alvarez# | 2.867 | 2064 | |
| 79 | John Walker# | 2.872 | 2057 | |
| 80 | Jorge Pérez | 2.877 | 2041 | |
| 81 | Dillon Nemeth# | 2.889 | 2065 | |
| 82 | Juan Reyes | 2.893 | 2047 | |
| 83 | Mamoru Fujihara | 2.901 | 2044 | |
| 84 | Andy Blomgren# | 2.908 | 2065 | |
| 85 | Horace O'Neill | 2.928 | 2050 | |
| 86 | Jesus Vargas# | 2.929 | 2065 | |
| 87 | Ryan Paul# | 2.930 | 2057 | |
| 88 | Gerjan Ramaekers# | 2.935 | 2058 | |
| 88 | Alec Goffe | 2.935 | 2041 | |
| 90 | Kei-thing Xiang# | 2.950 | 2053 | |
| 91 | Tony Stanley | 2.960 | 2042 | |
| 92 | Jeff Reddy | 2.961 | 2048 | |
| 93 | Jon Hester | 2.981 | 2049 | |
| 94 | Dave Kessler | 2.987 | 2034 | |
| 95 | Steve Miller | 2.988 | 2036 | |
| 96 | Louwe Roocke | 2.989 | 2024 | |
| 97 | Tim Gregg | 2.993 | 2049 | |
| 98 | Jeff Locke | 3.012 | 2042 | |
| 99 | Al West# | 3.013 | 2058 | |
| 100 | Ken Halliwell | 3.015 | 2014 |
