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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Saguilan, Ricky | C | Jupiter Spuds | 19 | 10/11/2050 | La Romana | DOM | Right | Right | 6' 2" | 200 lbs | - |
| Saiz, Eddie | RP | Free Agent | 21 | 02/15/2048 | Cataño | PUR | Left | Right | 6' 1" | 175 lbs | - |
| Sakaguchi, Tsuyoshi | RP | Free Agent | 19 | 02/21/2050 | Kawasaki | JPN | Left | Left | 6' 3" | 185 lbs | - |
| Sakai, Tadashige | SP | St. Cloud Silver Hawks | 21 | 07/27/2048 | Mitaka | JPN | Left | Left | 6' 6" | 200 lbs | - |
| Salazar, Antonio | RP | Gainesville Gators | 23 | 10/27/2046 | Oakley | USA | Left | Left | 6' 4" | 175 lbs | - |
| Salcido, Miguel | CF | Miami Aces | 20 | 03/04/2049 | Santiago | CHI | Right | Right | 6' 0" | 170 lbs | - |
| Salgado, David | SP | Delray Beach Grasshoppers | 21 | 08/14/2048 | Apodaca | MEX | Left | Right | 6' 1" | 190 lbs | - |
| Salgado, Jose | SP | Tallahassee Bandits | 21 | 05/17/2048 | San Salvador | SLV | Right | Right | 6' 0" | 170 lbs | - |
| Samano, Alberto | SS | Jacksonville Rockies | 21 | 09/12/2048 | Vega Baja | PUR | Right | Right | 5' 11" | 175 lbs | - |
| Sams, Chris | RP | Sanford Swamp Things | 24 | 09/25/2045 | Huntsville | USA | Left | Right | 6' 6" | 200 lbs | - |
| Sanchez, Estevan | RP | Free Agent | 21 | 05/02/2048 | Managua | NCA | Right | Right | 6' 0" | 180 lbs | - |
| Sanchez, Jay | SP | Jacksonville Rockies | 20 | 06/26/2049 | East Merrimack | USA | Left | Right | 6' 0" | 170 lbs | - |
| Sanchez, Vicente | RP | Bradenton Bucs | 21 | 05/22/2048 | Los Llanos | DOM | Right | Right | 6' 5" | 200 lbs | - |
| Sanderson, Bill | 1B | St. Cloud Silver Hawks | 24 | 11/05/2045 | San Jose | USA | Right | Right | 6' 2" | 205 lbs | - |
| Sandoval, Antonio | 1B | Kissimmee Rage | 21 | 11/21/2047 | Havana | CUB | Left | Right | 6' 4" | 200 lbs | - |
| Santana, Jose | 3B | Tallahassee Bandits | 21 | 01/31/2048 | San Juan | PUR | Switch | Right | 6' 1" | 190 lbs | - |
| Santiago, Carlos | SP | Ocala Pippins | 20 | 06/09/2049 | Arecibo | PUR | Right | Right | 6' 6" | 200 lbs | - |
| Santiago, Omar | CF | Jupiter Spuds | 18 | 07/12/2051 | Caracas | VEN | Left | Left | 6' 2" | 180 lbs | - |
| Santos, Juan | C | Miami Aces | 21 | 05/27/2048 | Lufkin | USA | Right | Right | 6' 4" | 205 lbs | - |
| Santos, Mario | SP | St. Augustine Suns | 21 | 03/21/2048 | Primero de Enero | CUB | Switch | Right | 6' 0" | 175 lbs | - |
| Sardina, Shigeyori | CF | Sunrise Gators | 20 | 09/23/2049 | Toyota | JPN | Right | Right | 5' 11" | 165 lbs | - |
| Saunders, Matt | SP | Orlando Oceanics | 18 | 01/20/2051 | Boardman | USA | Right | Right | 6' 1" | 175 lbs | - |
| Schaeffer, Marc | CF | St. Petersburg Crocodiles | 22 | 10/04/2047 | Gonaïves | HAI | Left | Left | 6' 2" | 190 lbs | - |
| Schneider, Jesse | 1B | Punta Gorda Bulldogs | 17 | 04/23/2052 | Boardman | USA | Right | Right | 6' 8" | 200 lbs | - |
| Schouten, Addick | C | Kissimmee Rage | 21 | 02/11/2048 | Willemstad | CUR | Right | Right | 6' 6" | 210 lbs | - |
| Schumann, Kasey | CF | Pensacola Wahoos | 20 | 11/24/2048 | Elkhart | USA | Right | Right | 6' 0" | 175 lbs | - |
| Secor, Danny | SP | Sanford Swamp Things | 20 | 08/20/2049 | Tracy | USA | Right | Right | 6' 6" | 190 lbs | - |
| Selvey, Aaron | 1B | Bradenton Bucs | 21 | 06/18/2048 | Anchorage | USA | Switch | Right | 6' 0" | 200 lbs | - |
| Serrano, Alfredo | CF | Bradenton Bucs | 21 | 12/23/2047 | Catia La Mar | VEN | Right | Right | 6' 2" | 185 lbs | - |
| Severino, Roberto | 2B | Free Agent | 19 | 03/09/2050 | Placetas | CUB | Right | Right | 6' 2" | 185 lbs | - |
| Shaw, Mike | SP | Jupiter Spuds | 19 | 09/22/2050 | Laguna Hills | USA | Left | Left | 6' 6" | 190 lbs | - |
| Sigala, Eduardo | RP | Free Agent | 20 | 05/10/2049 | Caracas | VEN | Right | Right | 6' 4" | 180 lbs | - |
| Silva, Robert | SP | Miami Aces | 18 | 08/26/2051 | Folsom | USA | Right | Right | 6' 2" | 175 lbs | - |
| Silva, Willie | CL | Sunrise Gators | 22 | 02/05/2047 | Maracaibo | VEN | Right | Right | 6' 6" | 205 lbs | - |
| Simon, David | C | Orlando Oceanics | 20 | 02/23/2049 | Calgary | CAN | Right | Right | 6' 2" | 180 lbs | - |
| Simpson, Mitch | SP | Kissimmee Rage | 20 | 04/26/2049 | Manhattan Beach | USA | Right | Right | 5' 10" | 170 lbs | - |
| Smith, Alan | CF | St. Augustine Suns | 20 | 03/15/2049 | Charlotte Amalie | VIR | Right | Right | 6' 1" | 175 lbs | - |
| Solis, Danny | RP | Gainesville Gators | 22 | 11/09/2047 | Coacalco | MEX | Left | Left | 6' 4" | 190 lbs | - |
| Soper, Geoff | RP | Sanford Swamp Things | 20 | 12/22/2048 | Agat | GUM | Right | Left | 6' 1" | 170 lbs | - |
| Sosa, Angelo | 1B | Tallahassee Bandits | 20 | 01/20/2049 | Alajuela | CRC | Left | Left | 6' 2" | 200 lbs | - |
| Sosa, Juan | CF | Miami Beach Expos | 19 | 04/15/2050 | Camagüey | CUB | Right | Right | 6' 1" | 185 lbs | - |
| Sotelo, Jorge | RP | St. Augustine Suns | 20 | 10/07/2049 | Spring Hill | USA | Switch | Right | 6' 6" | 195 lbs | - |
| Soto, Rafael | CF | Jacksonville Rockies | 20 | 06/19/2049 | Santo Domingo | DOM | Right | Right | 6' 2" | 195 lbs | - |
| Soto, Willie | SS | Bradenton Bucs | 19 | 05/11/2050 | Veracruz | PAN | Right | Right | 6' 3" | 185 lbs | - |
| Soule, Jon | SP | Gainesville Gators | 20 | 03/17/2049 | Belton | USA | Right | Right | 6' 3" | 180 lbs | - |
| Spencer, Josh | CF | Orlando Oceanics | 19 | 06/02/2050 | Huntington Beach | USA | Left | Left | 6' 3" | 175 lbs | - |
| Spreeuwenberg, Job | RP | Free Agent | 22 | 09/14/2047 | Groningen | NED | Right | Right | 6' 2" | 190 lbs | - |
| Squire, Dave | 2B | Orlando Oceanics | 23 | 05/05/2046 | Ottawa | CAN | Right | Right | 6' 0" | 185 lbs | - |
| Stephens, Beau | C | Sarasota Wolves | 17 | 05/23/2052 | Buffalo | USA | Right | Right | 6' 3" | 195 lbs | - |
| Stettler, Kenny | 2B | Sarasota Wolves | 18 | 06/05/2051 | Allentown | USA | Left | Right | 6' 2" | 185 lbs | - |
| Stola, Josh | RP | Gainesville Gators | 21 | 01/05/2048 | New Straitsville | USA | Right | Right | 6' 5" | 185 lbs | - |
| Strapp, Aaron | RP | Orlando Oceanics | 19 | 01/15/2050 | Cypress | USA | Left | Right | 6' 2" | 180 lbs | - |
| Strawser, Brian | CF | Miami Aces | 20 | 01/07/2049 | Arlington | USA | Right | Right | 5' 10" | 170 lbs | - |
| Striano, Steve | CL | St. Petersburg Crocodiles | 20 | 10/15/2049 | Weirton | USA | Right | Right | 6' 4" | 185 lbs | - |
| Strider, Dan | LF | St. Cloud Silver Hawks | 20 | 04/16/2049 | Warren | USA | Left | Left | 6' 2" | 185 lbs | - |
| Suzuki, Fumio | SP | Miami Beach Expos | 19 | 03/23/2050 | Sakaiminato | JPN | Left | Left | 5' 11" | 165 lbs | - |
| Swett, John | RP | Punta Gorda Bulldogs | 22 | 06/15/2047 | Raceland | USA | Right | Right | 6' 4" | 180 lbs | - |
